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Thyroxineis used to treat an underactivethyroid(hypothyroidism). It replaces or provides more thyroidhormone, which is normally produced by the thyroid gland.Low thyroidhormone levels can occur naturally or when the thyroid gland is injured byradiation/medicationsor removed by surgery. Having enough thyroid hormone is important for maintaining normal mental andphysical activity. In children, having enough thyroid hormone is important for normal mental and physical development.